Hataraku Saibou Black - Vol. 6 Ch. 33 - The Brain, Vitality, Atrophy

This is the worst type of depression, clinical depression. This is where the body actually suffers after prolonged depression. While medicine can be prescribed, unless it is treated from the state of mind, it will only come back.
 
Bro i didn’t know i had cute idol girls cheering me up from within
 
You mean someone lost the opportunity to become a sympathetic nerve vtuber?
 

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